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Leukemia: Advances in Research and Treatment

admin — Thu, 18 Mar 2010 21:19:29 +0000

Product Description
Leukemia continues to offer the scientist a unique opportunity to gain new knowledge about the malignant transformation. As a result, this multi-authored volume, devoted to advances which have occurred over the last seven years, provides the reader with an important new understanding of leukemia, but perhaps even more important, predicts analogous, new developments in the other malignant diagnoses. In this respect, this volume represents the cutting edge of cancer research. This text is unique in that it includes in a single volume the leading contributors to their respective fields covering what the editors feel are the major advances in our knowledge of the biology and therapy of leukemia over the l… More >>

Leukemia: Advances in Research and Treatment

admin — Tue, 16 Mar 2010 21:23:41 +0000

Leukemia – Herbal Treatment Pack

admin — Mon, 14 Dec 2009 23:22:20 +0000

360 Tablets Pack of Leukotab. A complete herbal course for Leukemia.
Simple pills based product for easy use.
90 day course for complete relief.
198 natural plant based ingredients.
Historically established formula with guaranteed results.

Product Description
Leukotab is a completely guaranteed and clinically proven herbal treatment for Leukemia. Its formulation consisting of purely natural ingredients based on the Unani (Greek) system of herbal medicine blended together in a specific proportion to fight and treat Leukemia effectively…. More >>

Chemotherapy – Drugs Used For Treatment

admin — Sat, 19 Sep 2009 06:10:07 +0000

The method of killing the cancer cells present the whole body or in particular part by passing anti-cancer drugs into the blood stream is called chemotherapy. It is also employed to prevent the spreading of cancer from part to another. It proves to be more efficient when it is used in the metastasis condition. In this condition the cancer spreads to all parts from where it has originated.

Each every chemotherapy agent has specific role depending upon the treatment and characteristics of the drug used. Most of them intervene with the DNA synthesis. Based on their features and treatment they are classified as alkylating agents, anti-metabolits, anthracyclines, antitumor antibiotics, monoclonal antibodies, platinums, or plant alkaloids.

Alkylating agents are the widely used drugs in the chemotherapy treatment. These drugs are effective through all phases of cell cycle. The alkylate agent acts directly on the DNA strands, breaks the strands and forms abnormal pairing, thus prevents the cell division taking place, and cells die off as a result of it.

Anti-metabolits are found to be useful in treating chronic problems and some cases of leukemia and for various tumors.

Anthracyclines drugs are obtained from natural resources. They work by producing free oxygen radicals which acts with the DNA strands and prevents the cell division.

Antitumor antibiotics are obtained from soil fungus streptomyces. It employs the free oxygen radicals for breaking the DNA strands and preventing cell division. Bleomycin is a commonly used antitumor antibiotic

Monoclonal antibodies, they are attach themselves with the tumor specific antigens and thus block the growth of the cell.

Platinums, they are also used to provide the DNA impairing and to stop the cell growth. But the setback is they can injure the kidneys as they are toxic.

Plant alkaloids, according to the name they are derived from plants. And they are used in cell specific cycles.

Leukemia – The “White Blood” Disease

admin — Thu, 08 Nov 2007 13:03:18 +0000

Leukemia or leukaemia meaning white blood (Greek leukos, “white”; aima, “blood”) is a cancer of the blood or bone marrow and is characterized by an abnormal growth of blood cells, usually white blood cells (leukocytes)and is split into its acute and chronic forms. It can affect the digestive tract, kidneys, lungs, or other parts of the body and can also collect in the ********* causing swelling. Leukemia is one of the most common cancers of children, But isn’t just a children’s disease, as many think. It is newly diagnosed in about 29,000 adults and 2000 children each year in the United States and has four main types and many sub-types of which only some of them are common among children. Leukemia that has spread to the brain may produce central nervous system effects, such as headaches, seizures, weakness, blurred vision, balance difficulties, or vomiting and the disease, or the chemotherapy used to treat it, can cause anemia.

Acute Leukemia

Acute leukemia is characterized by the rapid increase of immature blood cells, and is a potentially curable disease; However only a small number of patients are cured with current therapy. It begins with one or a few white blood cells that have a lost or damaged DNA sequence and gets worse very fast and may make you feel sick right away. It tends to develop suddenly, whereas some chronic varieties may exist for years before they are even diagnosed. Immediate treatment is required due to the rapid progression and accumulation of the malignant cells, which then spill over into the bloodstream and spread to other organs of the body. Whereas acute leukemia must be treated immediately, chronic forms are sometimes monitored for some time before treatment to ensure maximum effectiveness of therapy.

Chronic Leukemia

Chronic leukemia is distinguished by the excessive build up of relatively mature, but still abnormal, blood cells and often goes undetected for many years until it is identified in a routine blood test. It is more common between ages 40 and 70 and is rare among young people. It tends to gets worse slowly and may not cause symptoms for years. Like many other cancers, it is a disease of old age. Doctors often find chronic leukemia during a routine checkup, before there are any noticeable symptoms. In adults, the acute forms occur in those of all ages, whereas the chronic varieties tend to occur in people older than 40 years. Although slow-growing chronic leukemia may also be seen in children, it is very rare, accounting for fewer than 50 cases in children each year in the United States.

Treatment

Treatment of leukemia is complex and it depends on your age and health, the type and how far it has spread. Treatment is generally considered necessary when the patient shows signs and symptoms such as low blood cell counts. In general, ALL treatment is divided into several phases. In children, an intensive 6-month treatment program is needed after induction, followed by 2 years of maintenance chemotherapy. For children with low-risk, standard therapy usually consists of three drugs (prednisone, L-asparaginase, and vincristine) for the first month of treatment. High-risk patients receive higher drug doses plus treatment with extra chemotherapeutic agents. Follow-up therapy for ALL patients usually consists of: supportive care, such as intravenous nutrition and treatment with oral antibiotics.

In general, the indications for treatment are: falling hemoglobin or platelet count, progression to a later stage of disease, painful, disease-related overgrowth of lymph nodes or spleen, lymphocyte doubling time (an indicator of lymphocyte reproduction) of fewer than 12 months. Overall, the strategy is to control bone marrow and systemic (whole-body) disease while offering specific treatment for the central nervous system (CNS), if necessary. Consolidation or “maintenance” treatments may be given to prevent disease recurrence once remission has been achieved. Whatever the plan, it is important for the patient to understand the treatment that is being given and the reasons behind the choice.

Conclusion

Leukemia is a cancer of blood-forming cells in the bone marrow. These cells crowd out other types of blood cells produced by the bone marrow, including red blood cells, which carry oxygen to tissues throughout your body, and platelets, which help form blood clots. Leukemia cells can spread to the lymph nodes or other organs causing swelling and/or pain and can also collect in the kidney, liver and spleen, causing enlargement of these organs. They also can affect the lungs and other parts of the body. Acute forms can occur in children and young adults. Chronic forms mostly occurs in older people, but can theoretically occur in any age group.

There is no single known cause for all of the different types of leukemia. Studies have linked exposure to petrochemicals, such as benzene, and hair dyes to the development of some forms. Viruses have been linked to other forms. Until the cause or causes are found, there is no known way to prevent the occurrence of the disease. As of 1998, it is estimated that each year, approximately 30,800 individuals will be diagnosed with the disease in the United States and 21,700 individuals will die of the disease.